Radiation Therapy: How It Works and What You Should Know

Radiation therapy has emerged as a cornerstone in the multidisciplinary approach to cancer treatment. In India, with the rising incidence of various cancers, understanding the nuances of radiation therapy becomes imperative for patients and caregivers alike. This guide delves into the workings of radiation therapy, its benefits, potential side effects, and the advancements making it more effective and accessible in the Indian healthcare landscape.

What is Radiation Therapy?

Radiation therapy, also known as radiotherapy, utilizes high-energy particles or waves, such as X-rays, gamma rays, electron beams, or protons, to destroy or damage cancer cells. By damaging the DNA of these cells, radiation impedes their ability to grow and divide, leading to cell death. Importantly, while radiation affects both cancerous and normal cells, normal cells possess a superior ability to repair themselves, allowing for targeted treatment with minimal collateral damage.

Types of Radiation Therapy

  1. External Beam Radiation Therapy (EBRT):

    • The most common form, EBRT delivers radiation from a machine outside the body, directing high-energy beams at the cancer site.

    • Advanced techniques include:

      • 3D Conformal Radiation Therapy (3D-CRT): Uses imaging to target tumors precisely.

      • Intensity-Modulated Radiation Therapy (IMRT): Modulates radiation intensity for optimal dosing.

      • Image-Guided Radiation Therapy (IGRT): Utilizes imaging during treatment for accuracy.

      • Stereotactic Body Radiation Therapy (SBRT): Delivers high doses in fewer sessions, ideal for small tumors.

  2. Internal Radiation Therapy (Brachytherapy):

    • Involves placing radioactive sources directly inside or near the tumor.

    • Commonly used for cancers of the cervix, prostate, and breast.

  3. Systemic Radiation Therapy:

    • Involves administering radioactive substances orally or intravenously.

    • The radioactive material travels through the bloodstream to target cancer cells.

    • Example:

How Does Radiation Therapy Work?

Radiation therapy damages the DNA within cancer cells, hindering their ability to reproduce. Over time, these damaged cells die and are naturally eliminated by the body. The precision of modern radiation techniques ensures maximal impact on cancer cells while sparing surrounding healthy tissue.

Benefits of Radiation Therapy

  • Targeted Treatment: Advanced imaging and delivery techniques allow for precise targeting of tumors.

  • Non-Invasive: Especially in EBRT, the procedure is non-invasive, reducing recovery times.

  • Versatility: Can be used alone or in combination with surgery, chemotherapy, or immunotherapy.

  • Palliative Care: Effective in alleviating symptoms like pain or bleeding in advanced cancers.

Potential Side Effects

Side effects vary based on the treatment area, radiation dose, and individual patient factors. Common side effects include:

  • Fatigue: A prevalent side effect, often accumulating over the course of treatment.

  • Skin Changes: Redness, peeling, or darkening in the treated area.

  • Hair Loss: Occurs only in the area being treated.

  • Appetite Changes: Especially when treating areas like the abdomen.

  • Nausea or Diarrhea: Common when the stomach or pelvic areas are irradiated.

Most side effects are temporary and manageable with medical support.

Advancements in Radiation Therapy in India

India has witnessed significant advancements in radiation oncology:

  • Proton Therapy Centers: Facilities like the Tata Memorial Centre have introduced proton therapy, offering precise treatment with minimal side effects.

  • CyberKnife Technology: Available in select centers, it provides robotic radiosurgery for tumors in sensitive areas.

  • Increased Accessibility: Government initiatives have improved access to radiation therapy in tier-2 and tier-3 cities.

Radiation Therapy for Liver Cancer

Liver cancer poses unique challenges due to the organ’s sensitivity. Radiation therapy options include:

  • Stereotactic Body Radiation Therapy (SBRT): Delivers high doses over fewer sessions, minimizing exposure to healthy liver tissue.

  • Selective Internal Radiation Therapy (SIRT): Involves injecting radioactive beads into the liver’s blood supply, targeting tumors directly.

These techniques have shown promise in managing liver tumors, especially when surgery isn’t feasible.

Radiation therapy stands as a pivotal tool in the fight against cancer, offering targeted treatment with evolving precision. With advancements in technology and increased accessibility in India, patients have more options than ever. Consulting with a radiation oncologist can provide clarity on the best approach tailored to individual needs.

FAQs

  1. Is radiation therapy painful?

The procedure itself is painless. However, some side effects, like skin irritation or fatigue, may cause discomfort during or after treatment.

  1. How long does a typical radiation therapy session last?

While the actual radiation delivery takes only a few minutes, the entire session, including setup, may last 15 to 45 minutes.

  1. Can radiation therapy be used in conjunction with other treatments?

Yes, radiation therapy is often combined with surgery, chemotherapy, or immunotherapy to enhance treatment efficacy.